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GSKure Tel Aviv-Yafo

Therapeutic Target for Treating Neurogenetic Disorders

GSKure is an IP-based company that owns innovative proprietary GSK-3 peptide inhibitor drug candidates.The companys Kure products are based on a novel design of compounds that target a unique region at the GSK-3 protein surface termed the substrate binding site.

The substrate-competitive inhibitors (SCIs) show improved selectivity and low toxicity compared to traditional ATP-competitive inhibitors.GSKures novel SCI strategy for drug design offers significant advantages for clinical practice.

Professor Hagit Eldar-Finkelman of Tel Aviv University conducted pioneering studies in developing GSK-3 inhibitors and their therapeutic use in treating human disease.