GSKure is an IP-based company that owns innovative proprietary GSK-3 peptide inhibitor drug candidates.The companys Kure products are based on a novel design of compounds that target a unique region at the GSK-3 protein surface termed the substrate binding site.
The substrate-competitive inhibitors (SCIs) show improved selectivity and low toxicity compared to traditional ATP-competitive inhibitors.GSKures novel SCI strategy for drug design offers significant advantages for clinical practice.
Professor Hagit Eldar-Finkelman of Tel Aviv University conducted pioneering studies in developing GSK-3 inhibitors and their therapeutic use in treating human disease.